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Another, more detailed, analysis was undertaken by Juang and colleagues, who retrospectively evaluated a population of patients with severe CDAD during an epidemic period between July 2001 and July 2003. 34 During this period, 79 patients were identified with severe CDAD, 18 of whom were treated with IVIG. Pair-matching was utilized, and no significant difference was discovered in the number of colectomies or deaths with or without IVIG administration.

A single case report describes the use of steroids in a pediatric case of refractory CDAD.